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Reference:
1. Spruance SL, Stewart JC, Freeman DJ et al. Early application of topical idoxuridine in dimethyl sulfoxide shortens the course of herpes simplex labialis: a multicenter placebo-controlled trial. J Infect Dis. 1990; 161 (2 ): 191-7.
*On average, compared with historical data for untreated cold sores.